GENR { SUMX| The D. melanogaster gene zucchini, abbreviated as zuc, is reported here. It encodes a product involved in oogenesis (sensu Insecta). It has been mapped cytologically to 33B3--F2. There are 5 recorded alleles: 4 classical mutants (1 available from the public stock centers) and 1 wild-type. Mutations have been isolated which are female sterile. zuc is discussed in 6 references, dated between 1991 and 2001. These include at least one study of mutant phenotypes. } # EOR GENR { SUMX| The D. melanogaster gene zero population growth, abbreviated as zpg, is reported here. It has also been known in FlyBase as CG10125 and inx4. It encodes a product with innexin channel activity involved in germ cell development which is a component of the gap junction. It has been sequenced. It has been mapped cytologically to 65B5. It interacts genetically with bam, dpp and bgcn. There are 13 recorded alleles: 1 in vitro construct (not available from the public stock centers), 11 classical mutants (none available from the public stock centers) and 1 wild-type. Mutations have been isolated which affect the (with Df(3L)ZN47) testis, the (with Df(3L)CH12) ovary, the (with Df(3L)ZN47) male germline stem cell and 9 other listed tissues and are viable, male sterile, (with Df(3L)ZN47) male sterile and (with Df(3L)CH12) female sterile. zpg is discussed in 17 references (excluding sequence accessions), dated between 1998 and 2003. These include at least 3 studies of mutant phenotypes, one study of wild-type function and 4 molecular studies. Among findings on zpg mutants, flies mutant for zpg are viable but sterile with very small gonads. Among findings on zpg function, zpg is required for the survival of differentiating early germ cells during gametogenesis in both sexes. } # EOR GENR { SUMX| The D. melanogaster gene ziti is reported here. It encodes a product with molecular_function unknown involved in oogenesis (sensu Insecta) which is a component of the cellular_component unknown. It has been mapped cytologically to h47--h53L. There is one recorded allele, which is wild-type. ziti is discussed in 2 references, dated between 1997 and 2002. These include at least one study of wild-type function. Among findings on ziti function, ziti is specifically required during oogenesis to maintain nurse cell chromosome organization. } # EOR GENR { SUMX| The D. melanogaster gene ziplock is reported here. It encodes a product with molecular_function unknown involved in biological_process unknown which is a component of the cellular_component unknown. There is one recorded allele, which is wild-type. ziplock is discussed in 2 references, dated between 1998 and 2002. } # EOR GENR { SUMX| The D. melanogaster gene zipper, abbreviated as zip, is reported here. It has also been known in FlyBase as l(2)02957. It encodes a product with motor activity involved in muscle contraction which is a component of the Z disc; it is expressed in the embryo (embryonic central nervous system and mesoderm). It has been sequenced and its amino acid sequence contains a myosin head (motor domain). It has been mapped by recombination to 2-107 and cytologically to 60E11--12. It interacts genetically with Rho1, RhoGEF2, Sb, br, rok and 20 other listed genes. There are 22 recorded alleles: 5 in vitro constructs (none available from the public stock centers), 16 classical mutants (3 available from the public stock centers) and 1 wild-type. Amorphic mutations have been isolated which affect the embryonic nervous system, the peripheral nervous system, the central nervous system and 16 other listed tissues and are embryonic lethal and (with zip²) lethal. zip is discussed in 195 references (excluding sequence accessions), dated between 1983 and 2004. These include at least 26 studies of mutant phenotypes, 3 studies of wild-type function and 7 molecular studies. Among findings on zip mutants, zip mutant embryos display defects in dorsal closure, head involution, segmentation and neural pathfinding. Among findings on zip function, zip is necessary for normal morphology and beghavior of the leading edge cells during embryonic dorsal closure. } # EOR GENR { SUMX| The D. melanogaster gene Meiotic central spindle, abbreviated as Meics, is reported here. It has also been known in FlyBase as zinc-finger-motif-protein. It encodes a product with transcription factor activity involved in spermatogenesis which is a component of the spindle. It has been sequenced. It has been mapped cytologically to 70C7. There is one recorded allele, which is wild-type. Meics is discussed in 7 references (excluding sequence accessions), dated between 1999 and 2003. These include at least one molecular study. } # EOR GENR { SUMX| The D. melanogaster gene Zn finger homeodomain 2, abbreviated as zfh2, is reported here. It encodes a product with RNA polymerase II transcription factor activity involved in wing morphogenesis which is localized to the nucleus; it is expressed in the embryo (embryonic central nervous system and embryonic/larval hindgut) and larva (abdominal 3 neuroblast dorso-lateral cluster, abdominal 3 neuroblast ventro-lateral cluster, abdominal 4 neuroblast dorso-lateral cluster, abdominal 4 neuroblast ventro-lateral cluster and 7 other listed tissues). It has been sequenced and its amino acid sequence contains a RNA-binding protein C2H2 Zn-finger domain, a zinc finger, C2H2 type and a homeobox domain. It has been mapped cytologically to 102C2. There are 5 recorded alleles: 4 classical mutants (none available from the public stock centers) and 1 wild-type. Mutations have been isolated which affect the proximal wing and are poor viable. zfh2 is discussed in 39 references (excluding sequence accessions), dated between 1991 and 2003. These include at least 4 studies of mutant phenotypes, one study of wild-type function, one study of natural polymorphisms and 7 molecular studies. Among findings on zfh2 function, zfh2 is required for proximal wng development. } # EOR GENR { SUMX| The D. melanogaster gene Zn finger homeodomain 1, abbreviated as zfh1, is reported here. It encodes a product with RNA polymerase II transcription factor activity involved in mesoderm development which is localized to the nucleus; it is expressed in the embryo (RP neuron, VUM neuron, aCC neuron, adult myoblast and 13 other listed tissues). It has been sequenced and its amino acid sequence contains a zinc finger, C2H2 type and a homeobox domain. It has been mapped cytologically to 100A4--5. It interacts genetically with eve and tin. There are 28 recorded alleles: 7 in vitro constructs (3 available from the public stock centers), 20 classical mutants (1 available from the public stock centers) and 1 wild-type. Loss-of-function mutations have been isolated which affect the embryonic/larval dorsal vessel, the embryonic/larval somatic muscle and the pericardial cell and are embryonic recessive lethal. zfh1 is discussed in 102 references (excluding sequence accessions), dated between 1991 and 2004. These include at least 5 studies of mutant phenotypes, 5 studies of wild-type function and 10 molecular studies. Among findings on zfh1 function, zfh1 is required for the development of both fat body and gonadal mesoderm in the embryo. } # EOR GENR { SUMX| The D. melanogaster gene Zinc finger protein 30C, abbreviated as zf30C, is reported here. It has also been known in FlyBase as anon-1.52, anon-EST:Liang-1.52 and l(2)k02506. It encodes a product with transcription factor activity putatively involved in regulation of transcription from Pol II promoter which is a component of the nucleus. It has been sequenced. It has been mapped cytologically to 30C7. There are 5 recorded alleles: 4 classical mutants (1 available from the public stock centers) and 1 wild-type. Loss-of-function mutations have been isolated which affect the wing, the (with Df(2L)30A-C) wing, the (with Df(2L)30A-C) wing vein L5 and 7 other listed tissues and are visible, (with Df(2L)30A-C) visible, (with Df(2L)&ggr;7) visible, (with Df(2L)N22-3) visible, (with Df(2L)s1402) visible, (with Df(2L)30A-C) fertile, (with Df(2L)&ggr;7) fertile, (with Df(2L)N22-3) fertile, (with Df(2L)s1402) fertile, (with zf30C^EP518) fertile, (with zf30C^EP2228) fertile, (with zf30C^EP518) wild-type and (with zf30C^EP2228) wild-type. zf30C is discussed in 15 references (excluding sequence accessions), dated between 1994 and 2004. These include at least one study of mutant phenotypes and 5 molecular studies. Among findings on zf30C mutants, zf30C mutations cause wing and female fertility phenotypes, but not lethality. } # EOR GENR { SUMX| The D. melanogaster gene zerknullt-related, abbreviated as zen2, is reported here. It encodes a product with transcription factor activity involved in dorsal/ventral pattern formation, imaginal disc which is a component of the nucleus; it is expressed in the embryo (amnioserosa, dorsal ectoderm, dorsal fold and embryo). It has been sequenced and its amino acid sequence contains a helix-turn-helix / &lgr; and other repressors and a homeobox domain. It has been mapped by recombination to 3-47.5 and cytologically to 84A5. There are 14 recorded alleles: 13 in vitro constructs (none available from the public stock centers) and 1 wild-type. zen2 is discussed in 38 references (excluding sequence accessions), dated between 1987 and 2003. These include at least 5 molecular studies. } # EOR GENR { SUMX| The D. melanogaster gene zerknullt, abbreviated as zen, is reported here. It encodes a product with specific RNA polymerase II transcription factor activity involved in dorsal/ventral axis specification which is a component of the nucleus; it is expressed in the embryo (, dorsal ectoderm, pole cell and dorsal ectoderm). It has been sequenced and its amino acid sequence contains a homeobox domain. It has been mapped by recombination to 3-47.5 and cytologically to 84A5. It interacts genetically with tor, Mad, Med, dpp and sog. There are 20 recorded alleles: 11 in vitro constructs (none available from the public stock centers), 8 classical mutants (7 available from the public stock centers) and 1 wild-type. Loss-of-function mutations have been isolated which affect the optic lobe and are embryonic lethal. zen is discussed in 239 references (excluding sequence accessions), dated between 1980 and 2004. These include at least 30 studies of mutant phenotypes and 9 molecular studies. } # EOR GENR { SUMX| The D. melanogaster gene zarolho, abbreviated as zaro, is reported here. It encodes a product with molecular_function unknown involved in visual perception which is a component of the cellular_component unknown. It has been mapped cytologically to 71F. There is one recorded allele, which is wild-type. zaro is discussed in 3 references, dated between 1995 and 2002. } # EOR GENR { SUMX| The D. melanogaster gene zuker-aly-like b, abbreviated as zab, is reported here. It has been mapped cytologically to 58B1--2. There is one recorded allele, which is wild-type. zab is discussed in 4 references, dated between 1999 and 2001. } # EOR GENR { SUMX| The D. melanogaster gene zeste, abbreviated as z, is reported here. It encodes a product with DNA binding involved in regulation of transcription, DNA-dependent which is localized to the polytene chromosome; it is expressed in the adult (adult brain, adult muscle system, antenna and gonad), larva (Malpighian tubule, embryonic/larval digestive system, embryonic/larval salivary gland, gonad and 3 other listed tissues) and prepupa and pupa (adult abdomen). It has been sequenced and its amino acid sequence is also available. It has been mapped by recombination to 1-1.0 and cytologically to 3A3. It interacts genetically with w, E(z), Psc, M(2)21AB, Su(z)2 and 18 other listed genes. There are 83 recorded alleles: 40 in vitro constructs (none available from the public stock centers), 42 classical mutants (8 available from the public stock centers) and 1 wild-type. Amorphic mutations have been isolated which affect the pigment cell and are eye color defective and visible. z is discussed in 292 references (excluding sequence accessions), dated between 1948 and 2004. These include at least 50 studies of mutant phenotypes, 2 studies of wild-type function, 4 studies of natural polymorphisms and 9 molecular studies. Among findings on z mutants, the assembly of the z gene product into multimeric forms is an orderly, stepwise process which can be arrested at intermediate stages by mutations affecting the integrity or configuration of heptad repeats. Among findings on z function, c-terminal domain of the z protein is responsible for the extensive aggregation properties of the z protein that are required for its role in transvection phenomena. } # EOR GENR { SUMX| The D. melanogaster gene yurt, abbreviated as yrt, is reported here. It has also been known in FlyBase as CG9764 and l(3)87Ek. It encodes a product with putative cytoskeletal protein binding involved in dorsal closure. It has been sequenced. It has been mapped by recombination to 3-52 and cytologically to 87E11. There are 17 recorded alleles: 16 classical mutants (1 available from the public stock centers) and 1 wild-type. Mutations have been isolated which affect the macrochaeta and the ommatidium and are lethal. yrt is discussed in 23 references (excluding sequence accessions), dated between 1976 and 2003. These include at least 2 studies of mutant phenotypes, one study of wild-type function and 3 molecular studies. Among findings on yrt mutants, yrt mutants display failure of posterior dorsal closure. } # EOR GENR { SUMX| The D. melanogaster gene ypsilon schachtel, abbreviated as yps, is reported here. It encodes a product with nucleic acid binding involved in oogenesis (sensu Insecta) which is a component of the nucleus. It has been sequenced. It has been mapped cytologically to 68F4. It interacts genetically with orb. There are 2 recorded alleles: 1 classical mutant (not available from the public stock centers) and 1 wild-type. Loss-of-function mutations have been isolated which are viable, fertile, female fertile, (with Df(3L)BK9) viable and (with Df(3L)BK9) female fertile. yps is discussed in 29 references (excluding sequence accessions), dated between 1997 and 2003. These include at least 2 studies of mutant phenotypes and 2 molecular studies. } # EOR GENR { SUMX| The opus element (D. melanogaster) gene opus\pol is reported here. It has also been known in FlyBase as yoyo\Pol and yoyo\pol. It has been sequenced. There is one recorded allele, which is wild-type. opus\pol is discussed in one reference (excluding sequence accessions), dating from 1998. } # EOR GENR { SUMX| The opus element (D. melanogaster) gene opus\gag is reported here. It has also been known in FlyBase as yoyo\Gag and yoyo\gag. It has been sequenced. There is one recorded allele, which is wild-type. opus\gag is discussed in one reference (excluding sequence accessions), dating from 1998. } # EOR GENR { SUMX| The opus element (D. melanogaster) gene opus\env is reported here. It has also been known in FlyBase as yoyo\Env and yoyo\env. There is one recorded allele, which is wild-type. opus\env is discussed in 3 references, dated between 1998 and 2002. } # EOR GENR { SUMX| The D. melanogaster gene yande, abbreviated as ynd, is reported here. It has been mapped cytologically to 96D. There is one recorded allele, which is wild-type. ynd is discussed in 2 references, dated between 1996 and 1999. These include at least one study of wild-type function. } # EOR GENR { SUMX| The D. melanogaster gene yolkless, abbreviated as yl, is reported here. It encodes a product with vitellogenin receptor activity involved in oogenesis (sensu Insecta) which is expressed in the ovary (ovary). It has been sequenced and its amino acid sequence contains a calcium-binding EGF-like domain. It has been mapped by recombination to 1-48 and cytologically to 12E3--4. There are 37 recorded alleles: 1 in vitro construct (not available from the public stock centers), 35 classical mutants (2 available from the public stock centers) and 1 wild-type. Mutations have been isolated which affect the yolk granule and the female adult hemolymph and are female sterile soma-dependent and recessive female sterile. yl is discussed in 32 references (excluding sequence accessions), dated between 1975 and 2004. These include at least 3 studies of mutant phenotypes and 2 molecular studies. } # EOR GENR { SUMX| The D. melanogaster gene yin is reported here. It has also been known in FlyBase as opt1. It encodes a product with proton-dependent oligopeptide transporter activity putatively involved in transport which is a component of the integral to plasma membrane; it is expressed in the adult (alpha-lobe, adult antennal nerve, adult fat body, adult head and 13 other listed tissues), embryo (yolk) and ovary (nurse cell). It has been sequenced. It has been mapped cytologically to 3F3--4. There are 2 recorded alleles: 1 classical mutant (not available from the public stock centers) and 1 wild-type. yin is discussed in 18 references (excluding sequence accessions), dated between 1995 and 2003. These include at least one study of wild-type function and 8 molecular studies. } # EOR GENR { SUMX| The D. melanogaster gene furry, abbreviated as fry, is reported here. It has also been known in FlyBase as CG14171, CG6774, CG6780, l(3)02240 and yeti. It encodes a product involved in wing morphogenesis. It has been sequenced. It has been mapped cytologically to 67C2--4. It interacts genetically with sina. There are 9 recorded alleles: 8 classical mutants (1 available from the public stock centers) and 1 wild-type. Hypomorphic mutations have been isolated which affect the supernumerary wing hair, the triple row, the head bristle and 2 other listed tissues and are recessive lethal, (with fry⁷) visible and visible. fry is discussed in 17 references (excluding sequence accessions), dated between 1994 and 2004. These include at least 2 studies of mutant phenotypes, one study of wild-type function and 4 molecular studies. Among findings on fry mutants, mutations in fry result in branched arista laterals, branched bristles and a strong multiple wing hair phenotype. } # EOR GENR { SUMX| The D. melanogaster gene oncogene yes homologue 95CD, abbreviated as yes95CD, is reported here. It encodes a product with putative protein-tyrosine kinase activity (EC:2.7.1.112) putatively involved in protein amino acid phosphorylation. It has been mapped cytologically to 95C--D. There is one recorded allele, which is wild-type. yes95CD is discussed in 5 references, dated between 1989 and 1993. } # EOR GENR { SUMX| The D. melanogaster gene oncogene yes homologue 8D, abbreviated as yes8D, is reported here. It encodes a product with putative protein-tyrosine kinase activity (EC:2.7.1.112) putatively involved in protein amino acid phosphorylation. It has been mapped cytologically to 8D. There is one recorded allele, which is wild-type. yes8D is discussed in 5 references, dated between 1989 and 1993. } # EOR GENR { SUMX| The D. melanogaster gene oncogene yes homologue 57BC, abbreviated as yes57BC, is reported here. It encodes a product with putative protein-tyrosine kinase activity (EC:2.7.1.112) putatively involved in protein amino acid phosphorylation. It has been mapped cytologically to 57B--C. There is one recorded allele, which is wild-type. yes57BC is discussed in 5 references, dated between 1989 and 1993. } # EOR GENR { SUMX| The D. melanogaster gene yema gene 9.5, abbreviated as yemG9.5, is reported here. It encodes a product which is expressed in the adult (optic lobe, nurse cell and ovary), embryo (embryonic brain, embryonic central nervous system, ganglion mother cell and neuroblast), larva (ganglion mother cell, imaginal disc, neuroblast and spermatocyte) and prepupa and pupa (imaginal disc and cerebral cortex). It has been mapped cytologically to 98F6--7. There is one recorded allele, which is wild-type. yemG9.5 is discussed in 5 references, dated between 1987 and 1992. These include at least 3 molecular studies. } # EOR GENR { SUMX| The D. melanogaster gene yema gene 4, abbreviated as yemG4, is reported here. It encodes a product which is expressed in the adult (nurse cell, oocyte, ovary and ovary), embryo (embryonic proventriculus) and larva (central nervous system, hindgut, proventriculus, spermatocyte and imaginal disc). It has been mapped cytologically to 98F6--7. There is one recorded allele, which is wild-type. yemG4 is discussed in 5 references, dated between 1987 and 1992. These include at least 3 molecular studies. } # EOR GENR { SUMX| The D. melanogaster gene yema gene 3c, abbreviated as yemG3c, is reported here. It encodes a product which is expressed in the adult (ovary and ovary), embryo (central nervous system and lymph gland) and larva (hindgut, spermatocyte and imaginal disc). It has been mapped cytologically to 98F6--7. There is one recorded allele, which is wild-type. yemG3c is discussed in 5 references, dated between 1987 and 1992. These include at least 3 molecular studies. } # EOR GENR { SUMX| The D. melanogaster gene yema gene 3b, abbreviated as yemG3b, is reported here. It encodes a product which is expressed in the adult (ovary), embryo (central nervous system) and larva (hindgut, spermatocyte and imaginal disc). It has been mapped cytologically to 98F6--7. There is one recorded allele, which is wild-type. yemG3b is discussed in 5 references, dated between 1987 and 1992. These include at least 2 molecular studies. } # EOR GENR { SUMX| The D. melanogaster gene yema gene 3a, abbreviated as yemG3a, is reported here. It encodes a product which is expressed in the adult (ovary and ovary). It has been mapped cytologically to 98F6--7. There is one recorded allele, which is wild-type. yemG3a is discussed in 5 references, dated between 1987 and 1992. These include at least 3 molecular studies. } # EOR GENR { SUMX| The D. melanogaster gene yema gene 3.4, abbreviated as yemG3.4, is reported here. It encodes a product which is expressed in the adult (ovary and ovary). It has been mapped cytologically to 98F6--7. There is one recorded allele, which is wild-type. yemG3.4 is discussed in 5 references, dated between 1987 and 1992. These include at least 3 molecular studies. } # EOR GENR { SUMX| The D. melanogaster gene yema gene 2.8, abbreviated as yemG2.8, is reported here. It encodes a product which is expressed in the adult (ovary and ovary). It has been mapped cytologically to 98F6--7. There is one recorded allele, which is wild-type. yemG2.8 is discussed in 5 references, dated between 1987 and 1992. These include at least 3 molecular studies. } # EOR GENR { SUMX| The D. melanogaster gene yemanuclein &agr;, abbreviated as yem&agr;, is reported here. It has also been known in FlyBase as CG14513. It encodes a product with DNA binding involved in oogenesis (sensu Insecta) which is a component of the nucleus. It has been sequenced and its amino acid sequence is also available. It has been mapped cytologically to 98F10. There is one recorded allele, which is wild-type. yem&agr; is discussed in 21 references (excluding sequence accessions), dated between 1987 and 2003. These include at least 4 molecular studies. } # EOR GENR { SUMX| The D. melanogaster gene yeast 7, abbreviated as yea7, is reported here. It has been mapped by recombination to 1-53. There are 2 recorded alleles: 1 classical mutant (not available from the public stock centers) and 1 wild-type. yea7 is discussed in 2 references, dated between 1974 and 1992. } # EOR GENR { SUMX| The D. melanogaster gene yeast 6, abbreviated as yea6, is reported here. It has been mapped by recombination to 1-45. There are 2 recorded alleles: 1 classical mutant (not available from the public stock centers) and 1 wild-type. yea6 is discussed in 2 references, dated between 1974 and 1992. } # EOR GENR { SUMX| The D. melanogaster gene yeast 5, abbreviated as yea5, is reported here. It has been mapped by recombination to 1-66. There are 2 recorded alleles: 1 classical mutant (not available from the public stock centers) and 1 wild-type. yea5 is discussed in 2 references, dated between 1974 and 1992. } # EOR GENR { SUMX| The D. melanogaster gene yeast 4, abbreviated as yea4, is reported here. It has been mapped by recombination to 1-3--5. There are 3 recorded alleles: 2 classical mutants (none available from the public stock centers) and 1 wild-type. yea4 is discussed in 2 references, dated between 1974 and 1992. } # EOR GENR { SUMX| The D. melanogaster gene yeast 3, abbreviated as yea3, is reported here. It has been mapped by recombination to 1-0.8. There are 2 recorded alleles: 1 classical mutant (not available from the public stock centers) and 1 wild-type. yea3 is discussed in 2 references, dated between 1974 and 1992. } # EOR GENR { SUMX| The D. melanogaster gene yeast 2, abbreviated as yea2, is reported here. It has been mapped by recombination to 1-16. There are 2 recorded alleles: 1 classical mutant (not available from the public stock centers) and 1 wild-type. yea2 is discussed in 2 references, dated between 1974 and 1992. } # EOR GENR { SUMX| The D. melanogaster gene yeast 1, abbreviated as yea1, is reported here. It has been mapped by recombination to 1-37. There are 2 recorded alleles: 1 classical mutant (not available from the public stock centers) and 1 wild-type. yea1 is discussed in 2 references, dated between 1974 and 1992. } # EOR GENR { SUMX| The D. melanogaster gene y5-5 is reported here. There is one recorded allele, which is wild-type. y5-5 is discussed in 2 references, both dating from 1997. These include at least one study of wild-type function. } # EOR GENR { SUMX| The D. melanogaster gene y3-9 is reported here. There is one recorded allele, which is wild-type. y3-9 is discussed in one reference, dating from 1997. } # EOR GENR { SUMX| The D. melanogaster gene yellow, abbreviated as y, is reported here. It encodes a product with putative receptor binding involved in cuticle pigmentation which is a component of the extracellular; it is expressed in the adult (cuticle), embryo (Keilin's organ, abdominal segment 1 to 8, anal plate, cephalopharyngeal skeleton and 5 other listed tissues) and prepupa and pupa (epidermis). It has been sequenced and its amino acid sequence is also available. It has been mapped by recombination to 1-0.0 and cytologically to 1A5. It interacts genetically with su(Hw), mod(mdg4), dvr, e(y)1 to 3, e(y)6 and 6 other listed genes. There are 861 recorded alleles: 105 in vitro constructs (4 available from the public stock centers), 741 classical mutants (17 available from the public stock centers) and 15 wild-type. Amorphic mutations have been isolated which affect the (with y^TDH-370) adult cuticle(with y^TD82f-1) adult cuticle, the (with y^TDH-370) wing(with y^TD82f-1) wing, the (with y^TDH-376) adult cuticle(with y^TD82f-2) adult cuticle and 151 other listed tissues and are (with y^{TD82f-1 to 9}) body color defective, (with y^82f29) body color defective, (with y^{TD2-1 to 9}) body color defective, (with y²) body color defective, (with y^TDF) body color defective, (with y^{TDF-1 to 2}) body color defective, (with y^TDH+165) body color defective, (with y^TDH+161) body color defective, (with y^TDH+105) body color defective, (with y^TDH+51) body color defective, (with y^TDH+48) body color defective, (with y^TDH+36) body color defective, (with y^TDH+1) body color defective, (with y^{TDH-4b< y is discussed in 594 references (excluding sequence accessions), dated between 1916 and 2004. These include at least 30 studies of mutant phenotypes, 3 studies of wild-type function, 3 studies of natural polymorphisms and 11 molecular studies. Among findings on y function, y is necessary for normal male courtship and plays a role in the development of adult male wing extension during courtship.
}
# EOR
GENR
{
SUMX| The D. melanogaster gene extra wing hairs, abbreviated as xwh, is reported here. It has been mapped by recombination to 3-45. There are 2 recorded alleles: 1 classical mutant (not available from the public stock centers) and 1 wild-type. xwh is discussed in 2 references, dated between 1980 and 1992.
}
# EOR
GENR
{
SUMX| The D. melanogaster gene xmas-1 is reported here. It has also been known in FlyBase as CG8919 and xmas. It encodes a product involved in oogenesis (sensu Insecta). It has been sequenced. It has been mapped cytologically to 15E7. There are 9 recorded alleles: 8 classical mutants (1 available from the public stock centers) and 1 wild-type. Hypomorphic mutations have been isolated which are male sterile. xmas-1 is discussed in 10 references (excluding sequence accessions), dated between 1993 and 2002. These include at least one study of mutant phenotypes and 3 molecular studies.
}
# EOR
GENR
{
SUMX| The D. melanogaster repetitive element xerox is reported here. There is one recorded allele, which is wild-type. xerox is discussed in one reference, dating from 1995.
}
# EOR
GENR
{
SUMX| The D. melanogaster gene xenicid, abbreviated as xen, is reported here. It has been mapped cytologically to 51A5--C1. There are 2 recorded alleles: 1 classical mutant (available from the public stock centers) and 1 wild-type. Mutations have been isolated which affect the somatic clone wing and the larva and are larval recessive lethal and somatic clone visible. xen is discussed in 3 references, dated between 1997 and 2001.
}
# EOR
GENR
{
SUMX| The D. melanogaster gene x8 is reported here. There are 2 recorded alleles: 1 classical mutant (not available from the public stock centers) and 1 wild-type. x8 is discussed in 3 references, dated between 1970 and 1993.
}
# EOR
GENR
{
SUMX| The D. melanogaster gene x6 is reported here. There are 2 recorded alleles: 1 classical mutant (not available from the public stock centers) and 1 wild-type. x6 is discussed in 2 references, dated between 1969 and 1992.
}
# EOR
GENR
{
SUMX| The D. melanogaster gene x5 is reported here. There are 2 recorded alleles: 1 classical mutant (not available from the public stock centers) and 1 wild-type. x5 is discussed in 2 references, dated between 1969 and 1992.
}
# EOR
GENR
{
SUMX| The D. melanogaster gene x4 is reported here. There are 2 recorded alleles: 1 classical mutant (not available from the public stock centers) and 1 wild-type. x4 is discussed in 2 references, dated between 1969 and 1992.
}
# EOR
GENR
{
SUMX| The D. melanogaster gene x3 is reported here. There are 2 recorded alleles: 1 classical mutant (not available from the public stock centers) and 1 wild-type. x3 is discussed in 2 references, dated between 1969 and 1992.
}
# EOR
GENR
{
SUMX| The D. melanogaster gene x2 is reported here. There are 2 recorded alleles: 1 classical mutant (not available from the public stock centers) and 1 wild-type. x2 is discussed in 2 references, dated between 1969 and 1992.
}
# EOR
GENR
{
SUMX| The D. melanogaster gene x10 is reported here. There are 2 recorded alleles: 1 classical mutant (not available from the public stock centers) and 1 wild-type. x10 is discussed in 3 references, dated between 1970 and 1993.
}
# EOR
GENR
{
SUMX| The D. melanogaster gene x1 is reported here. There are 2 recorded alleles: 1 classical mutant (not available from the public stock centers) and 1 wild-type. x1 is discussed in 3 references, dated between 1969 and 1993.
}
# EOR
GENR
{
SUMX| The D. melanogaster gene wizened, abbreviated as wz, is reported here. It has been mapped by recombination to 3-47.8. There are 2 recorded alleles: 1 classical mutant (not available from the public stock centers) and 1 wild-type. Mutations have been isolated which affect the macrochaeta and are recessive sterile, recessive visible and body color defective. wz is discussed in 2 references, dated between 1923 and 1992.
}
# EOR
GENR
{
SUMX| The D. melanogaster gene wavy, abbreviated as wy, is reported here. It has been mapped by recombination to 1-40.7 and cytologically to 11D9--10. There are 8 recorded alleles: 7 classical mutants (3 available from the public stock centers) and 1 wild-type. Mutations have been isolated which affect the wing and are visible. wy is discussed in 18 references, dated between 1928 and 1997. These include at least one molecular study.
}
# EOR
GENR
{
SUMX| The D. melanogaster gene waxy, abbreviated as wx, is reported here. It has been mapped by recombination to 2-69.7. There are 3 recorded alleles: 2 classical mutants (1 available from the public stock centers) and 1 wild-type. Mutations have been isolated which affect the wing and are male sterile and female fertile. wx is discussed in 4 references, dated between 1942 and 1997.
}
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GENR
{
SUMX| The D. melanogaster gene wrong way, abbreviated as wwy, is reported here. It encodes a product with molecular_function unknown involved in axonogenesis which is a component of the cellular_component unknown. There are 7 recorded alleles: 6 classical mutants (none available from the public stock centers) and 1 wild-type. Mutations have been isolated which affect the commissure and the longitudinal connective. wwy is discussed in 5 references, dated between 1994 and 2002. These include at least one study of mutant phenotypes.
}
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GENR
{
SUMX| The D. melanogaster gene wider wing, abbreviated as ww, is reported here. It has been mapped by recombination to 1-32.9. There are 3 recorded alleles: 2 classical mutants (none available from the public stock centers) and 1 wild-type. Mutations have been isolated which affect the wing and are recessive visible, male viable, reduced female fertile and male fertile. ww is discussed in 2 references, dated between 1958 and 1992.
}
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GENR
{
SUMX| The D. melanogaster gene wv is reported here. It has been mapped by recombination to 1-41.9. There are 2 recorded alleles: 1 classical mutant (not available from the public stock centers) and 1 wild-type. Mutations have been isolated which affect the wing and are visible. wv is discussed in one reference, dating from 1941.
}
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GENR
{
SUMX| The D. melanogaster gene wings up A, abbreviated as wupA, is reported here. It has also been known in FlyBase as MS:DROTROPONI. It encodes a product with tropomyosin binding involved in neurogenesis which is a component of the troponin complex; it is expressed in the embryo (mesoderm) and larva (indirect flight muscle and tubular muscle). It has been sequenced and its amino acid sequence is also available. It has been mapped cytologically to 16F7. It interacts genetically with Mhc, Tm2, Actn, up, ari-1 and 6 other listed genes. There are 26 recorded alleles: 4 in vitro constructs (none available from the public stock centers), 21 classical mutants (none available from the public stock centers) and 1 wild-type. Loss-of-function mutations have been isolated which affect the nerve and are embryonic dominant lethal, recessive behavioral and neurophysiology defective. wupA is discussed in 56 references (excluding sequence accessions), dated between 1982 and 2004. These include at least 10 studies of mutant phenotypes, one study of wild-type function and 6 molecular studies. Among findings on wupA mutants, viable mutations of wupA cause selective degeneration of adult thoracic muscles.
}
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GENR
{
SUMX| The D. melanogaster gene wunen, abbreviated as wun, is reported here. It encodes a product with phosphatidate phosphatase activity (EC:3.1.3.4) involved in dephosphorylation which is a component of the integral to membrane; it is expressed in the embryo (ectoderm, embryonic central nervous system, hindgut primordium and posterior midgut primordium). It has been sequenced. It has been mapped cytologically to 45D3--4. There are 15 recorded alleles: 3 in vitro constructs (none available from the public stock centers), 11 classical mutants (4 available from the public stock centers) and 1 wild-type. Loss-of-function mutations have been isolated which affect the germ cell and are female sterile. wun is discussed in 53 references (excluding sequence accessions), dated between 1994 and 2004. These include at least 3 studies of mutant phenotypes, one study of wild-type function and 9 molecular studies. Among findings on wun function, wun and wun2 appear to act redundantly.
}
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GENR
{
SUMX| The D. melanogaster gene water wings, abbreviated as wtw, is reported here. It has been mapped by recombination to 1-38.9. There are 3 recorded alleles: 2 classical mutants (none available from the public stock centers) and 1 wild-type. Mutations have been isolated which affect the wing, the crossvein, the eye and 2 other listed tissues and are recessive visible, reduced viable and recessive female sterile. wtw is discussed in 2 references, dated between 1958 and 1992.
}
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GENR
{
SUMX| The D. melanogaster gene warts, abbreviated as wts, is reported here. It encodes a product with protein serine/threonine kinase activity involved in negative regulation of cell proliferation. It has been sequenced and its amino acid sequence contains an eukaryotic protein kinase, a protein kinase C-terminal domain and a serine/Threonine protein kinase family active site. It has been mapped cytologically to 100A5. It interacts genetically with CycA and cdc2. There are 84 recorded alleles: 4 in vitro constructs (none available from the public stock centers), 78 classical mutants (1 available from the public stock centers) and 2 wild-type. Amorphic mutations have been isolated which affect the ectopic pigment cell and are recessive lethal, somatic clone cell death decrease and somatic clone cell cycle. wts is discussed in 72 references (excluding sequence accessions), dated between 1992 and 2004. These include at least 6 studies of mutant phenotypes, one study of wild-type function and 4 molecular studies. Among findings on wts mutants, mitotic recombination clones homozygous for deficiencies of wts show overgrowth and abnormal morphogenesis indicating that wts is a tumor suppressor gene.
}
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GENR
{
SUMX| The D. melanogaster gene weltlike, abbreviated as wtl, is reported here. It has been mapped by recombination to 3-59.5. There are 2 recorded alleles: 1 classical mutant (not available from the public stock centers) and 1 wild-type. Mutations have been isolated which affect the eye, the arista and the wing and are female sterile. wtl is discussed in one reference, dating from 1992.
}
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GENR
{
SUMX| The D. melanogaster gene welt, abbreviated as wt, is reported here. It has been mapped by recombination to 2-85.3 and cytologically to 55C1--13. There are 3 recorded alleles: 2 classical mutants (1 available from the public stock centers) and 1 wild-type. Mutations have been isolated which affect the eye, the macrochaeta, the postvertical bristle and 2 other listed tissues. wt is discussed in 5 references, dated between 1977 and 1992.
}
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GENR
{
SUMX| The D. melanogaster gene waisted, abbreviated as ws, is reported here. It has been mapped by recombination to 1-1.0. There are 3 recorded alleles: 2 classical mutants (none available from the public stock centers) and 1 wild-type. Mutations have been isolated which affect the adult abdomen and the wing and are recessive visible and poor viable. ws is discussed in 2 references, dated between 1958 and 1992.
}
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GENR
{
SUMX| The D. melanogaster gene whirligig, abbreviated as wrl, is reported here. It encodes a product involved in sperm axoneme assembly. It has been mapped by recombination to 3-54.4 and cytologically to 88C2--D6. It interacts genetically with &bgr;Tub85D. There are 5 recorded alleles: 4 classical mutants (none available from the public stock centers) and 1 wild-type. Mutations have been isolated which affect the spermatid axoneme and are recessive male sterile and viable. wrl is discussed in 11 references, dated between 1980 and 1995. These include at least 2 studies of mutant phenotypes.
}
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GENR
{
SUMX| The D. melanogaster gene wrapper is reported here. It encodes a product involved in gliogenesis which is a component of the extrinsic to plasma membrane; it is expressed in the embryo (glial cell and midline glial cell) and larva (PNS glial cell, larval brain and ventral midline). It has been sequenced. It has been mapped cytologically to 58D4. There are 14 recorded alleles: 1 in vitro construct (not available from the public stock centers), 12 classical mutants (none available from the public stock centers) and 1 wild-type. Mutations have been isolated which affect the ventral nerve cord commissure. wrapper is discussed in 24 references (excluding sequence accessions), dated between 1998 and 2003. These include at least one study of mutant phenotypes and 4 molecular studies. Among findings on wrapper mutants, the midline glia migrate normally in wrapper mutant embryos, but they do not ensheath the commissural axons, and as a result die.
}
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GENR
{
SUMX| The D. melanogaster gene warped, abbreviated as wp, is reported here. It has been mapped by recombination to 3-47.5. There are 3 recorded alleles: 2 classical mutants (1 available from the public stock centers) and 1 wild-type. Mutations have been isolated which are recessive viable, male sterile and dominant visible. wp is discussed in 3 references, dated between 1923 and 1992.
}
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GENR
{
SUMX| The D. melanogaster gene without children, abbreviated as woc, is reported here. It has also been known in FlyBase as CG5965. It encodes a product with putative transcription regulator activity involved in ecdysone biosynthesis. It has been sequenced. It has been mapped cytologically to 97E11--F1. There are 4 recorded alleles: 1 in vitro construct (not available from the public stock centers), 2 classical mutants (none available from the public stock centers) and 1 wild-type. Mutations have been isolated which affect the ring gland, the prothoracic gland, the chromosome and 5 other listed tissues and are recessive lethal and (with woc^st1) sterile. woc is discussed in 7 references (excluding sequence accessions), dated between 1993 and 2003. These include at least one study of wild-type function and 2 molecular studies. Among findings on woc function, woc is essential for normal ecdysone biosynthesis.
}
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GENR
{
SUMX| The D. melanogaster gene wobbly B, abbreviated as wobB, is reported here. It has been mapped by recombination to 1-50. There are 2 recorded alleles: 1 classical mutant (not available from the public stock centers) and 1 wild-type. Mutations have been isolated which are uncoordinated. wobB is discussed in 3 references, dated between 1973 and 1992.
}
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GENR
{
SUMX| The D. melanogaster gene wobbly A, abbreviated as wobA, is reported here. There are 2 recorded alleles: 1 classical mutant (not available from the public stock centers) and 1 wild-type. Mutations have been isolated which are uncoordinated. wobA is discussed in 3 references, dated between 1973 and 1992.
}
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GENR
{
SUMX| The D. melanogaster gene white ocelli, abbreviated as wo, is reported here. It has been mapped by recombination to 3-76.2 and cytologically to 94A1--E2. There are 3 recorded alleles: 2 classical mutants (1 available from the public stock centers) and 1 wild-type. Mutations have been isolated which affect the ocellus pigment granule and are recessive visible. wo is discussed in 7 references, dated between 1920 and 1997.
}
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GENR
{
SUMX| The D. melanogaster gene wolf, abbreviated as wlf, is reported here. There is one recorded allele, which is wild-type. wlf is discussed in 2 references, both dating from 1999. These include at least one study of wild-type function.
}
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GENR
{
SUMX| The D. melanogaster gene whirly, abbreviated as wl, is reported here. There are 2 recorded alleles: 1 classical mutant (not available from the public stock centers) and 1 wild-type. Mutations have been isolated which affect the acrostichal bristle and are visible. wl is discussed in 2 references, dated between 1946 and 1992.
}
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GENR
{
SUMX| The D. melanogaster gene weak, abbreviated as wk, is reported here. It has been mapped by recombination to 3-42. There are 2 recorded alleles: 1 classical mutant (available from the public stock centers) and 1 wild-type. Mutations have been isolated which affect the macrochaeta, the wing and the abdomen and are reduced viable. wk is discussed in one reference, dating from 1992.
}
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GENR
{
SUMX| The D. melanogaster gene with trident, abbreviated as with, is reported here. There are 2 recorded alleles: 1 classical mutant (not available from the public stock centers) and 1 wild-type. Mutations have been isolated which affect the scutum. with is discussed in 4 references, dated between 1919 and 1996.
}
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GENR
{
SUMX| The D. melanogaster gene wishful thinking, abbreviated as wit, is reported here. It has also been known in FlyBase as CG10776, SE20, Stk-D, l(3)64Aa and l(3)S126215. It encodes a product with type II transforming growth factor beta receptor activity involved in protein amino acid phosphorylation which is a component of the plasma membrane. It has been sequenced. It has been mapped cytologically to 64A5. It interacts genetically with spin, Fmrf, Med, Mad, hiw and 3 other listed genes. There are 27 recorded alleles: 14 in vitro constructs (none available from the public stock centers), 12 classical mutants (2 available from the public stock centers) and 1 wild-type. Loss-of-function mutations have been isolated which affect the (with wit^HA5) bouton, the (with wit^HA5) larval muscle system and the (with wit^HA5) neuromuscular junction and are (with wit^HA5) neuroanatomy defective. wit is discussed in 43 references (excluding sequence accessions), dated between 1994 and 2004. These include at least 4 studies of mutant phenotypes, 4 studies of wild-type function and 5 molecular studies. Among findings on wit function, wit appears to function as a presynaptic receptor that regulates synaptic size at the neuromuscular junction.
}
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GENR
{
SUMX| The D. melanogaster gene wispy, abbreviated as wisp, is reported here. It has also been known in FlyBase as fs(1)M19. It encodes a product involved in female meiotic spindle assembly (sensu Animalia) which is putatively a component of the microtubule associated complex. It has been mapped by recombination to 1-37 and cytologically to 10F1--7. There are 14 recorded alleles: 13 classical mutants (1 available from the public stock centers) and 1 wild-type. Amorphic mutations have been isolated which affect the maternal effect egg, the ectopic spindle, the first meiotic metaphase and 4 other listed tissues and are recessive female sterile, embryonic maternal effect recessive lethal, recessive mitotic and recessive meiotic. wisp is discussed in 9 references, dated between 1977 and 2003. These include at least 2 studies of mutant phenotypes and 2 studies of wild-type function.
}
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GENR
{
SUMX| The D. melanogaster gene witty eye, abbreviated as wi, is reported here. It has been mapped by recombination to 2-55.0. There are 2 recorded alleles: 1 classical mutant (not available from the public stock centers) and 1 wild-type. Mutations have been isolated which affect the eye, the ommatidium and the vibrissae. wi is discussed in 3 references, dated between 1963 and 1992.
}
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GENR
{
SUMX| The D. melanogaster gene white head, abbreviated as whh, is reported here. There are 2 recorded alleles: 1 classical mutant (not available from the public stock centers) and 1 wild-type. Mutations have been isolated which affect the ocellus. whh is discussed in 2 references, dated between 1923 and 1992.
}
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GENR
{
SUMX| The D. melanogaster gene whiting, abbreviated as whg, is reported here. There are 2 recorded alleles: 1 classical mutant (not available from the public stock centers) and 1 wild-type. Mutations have been isolated which affect the eye and are eye color defective. whg is discussed in 3 references, dated between 1916 and 1992.
}
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GENR
{
SUMX| The D. melanogaster gene withered, abbreviated as whd, is reported here. It has been mapped by recombination to 2-61. There are 3 recorded alleles: 2 classical mutants (1 available from the public stock centers) and 1 wild-type. Mutations have been isolated which affect the wing. whd is discussed in 5 references, dated between 1968 and 1995.
}
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GENR
{
SUMX| The D. melanogaster gene whiskers, abbreviated as wh, is reported here. There are 2 recorded alleles: 1 classical mutant (not available from the public stock centers) and 1 wild-type. Mutations have been isolated which affect the vibrissae and are visible. wh is discussed in 2 references, dated between 1963 and 1992.
}
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GENR
{
SUMX| The D. melanogaster gene wing variance, abbreviated as wgv, is reported here. It has been mapped by recombination to 1-33.0. There are 2 recorded alleles: 1 classical mutant (not available from the public stock centers) and 1 wild-type. Mutations have been isolated which affect the wing and are visible, male sterile and male viable. wgv is discussed in 2 references, dated between 1959 and 1992.
}
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GENR
{
SUMX| The D. melanogaster gene wings out, abbreviated as wgo, is reported here. It has been mapped by recombination to 1-16.2. There are 2 recorded alleles: 1 classical mutant (not available from the public stock centers) and 1 wild-type. Mutations have been isolated which affect the wing. wgo is discussed in 2 references, dated between 1968 and 1992.
}
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GENR
{
SUMX| The D. melanogaster gene wingless, abbreviated as wg, is reported here. It has also been known in FlyBase as Gla, Sp and spd. It encodes a product with frizzled-2 binding involved in wing margin morphogenesis which is localized to the cytoplasm; it is expressed in the embryo (Malpighian tubule, analia, antennal segment, embryonic central nervous system and 16 other listed tissues) and larva (dorsal mesothoracic disc, dorsal metathoracic disc and ventral thoracic disc). It has been sequenced and its amino acid sequence contains a developmental signaling protein, Wnt-1 family. It has been mapped by recombination to 2-21.9 and cytologically to 27F1. It interacts genetically with fz2, dsh, N, vg, fz and 54 other listed genes. There are 218 recorded alleles: 91 in vitro constructs (1 available from the public stock centers), 122 classical mutants (15 available from the public stock centers) and 5 wild-type. Amorphic mutations have been isolated which affect the epidermis, the denticle belt and the antenna and are recessive lethal and recessive visible. wg is discussed in 1792 references (excluding sequence accessions), dated between 1923 and 2004. These include at least 110 studies of mutant phenotypes, 125 studies of wild-type function and 113 molecular studies. Among findings on wg mutants, low temperature fails to rescue heteroallelic combinations of wg¹ or wg^l-18 with the temperature-sensitive allele wg^l-12 after the larval stages. Among findings on wg function, downregulation of wg in the wing disc is essential for its development. (However, there is much more information on function so that may not be representative.)
}
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GENR
{
SUMX| The D. melanogaster gene weniger, abbreviated as weg, is reported here. It has also been known in FlyBase as weniger. It encodes a product involved in central nervous system development. It has been mapped by recombination to 1-0--1.15. There are 3 recorded alleles: 2 classical mutants (none available from the public stock centers) and 1 wild-type. Mutations have been isolated which affect the midline glial cell and the commissure. weg is discussed in 3 references, dated between 1999 and 2001. These include at least one study of mutant phenotypes.
}
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GENR
{
SUMX| The D. melanogaster gene wee is reported here. It encodes a product with protein kinase activity (EC:2.7.1.37) involved in mitotic cell cycle, embryonic which is localized to the nucleus; it is expressed in the embryo (embryonic central nervous system, embryonic/larval foregut, embryonic/larval hindgut, embryonic/larval midgut and 2 other listed tissues) and larva (larval brain). It has been sequenced. It has been mapped cytologically to 27C4. It interacts genetically with mei-41, cdc2, p53, trbl and Pten. There are 10 recorded alleles: 5 in vitro constructs (none available from the public stock centers), 4 classical mutants (2 available from the public stock centers) and 1 wild-type. Amorphic mutations have been isolated which are recessive female sterile, male fertile, embryonic non-rescuable maternal effect recessive lethal and (with Df(2L)Dwee1-W05) chemical sensitive. wee is discussed in 39 references (excluding sequence accessions), dated between 1993 and 2004. These include at least 3 studies of mutant phenotypes, one study of wild-type function and 7 molecular studies. Among findings on wee function, wee is zygotically dispensable but is required maternally for completing the nuclear division cycles of early embryogenesis.
}
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GENR
{
SUMX| The D. melanogaster gene wee, abbreviated as we, is reported here. It has been mapped by recombination to 1-3.0. There are 2 recorded alleles: 1 classical mutant (not available from the public stock centers) and 1 wild-type. Mutations have been isolated which affect the eye, the macrochaeta and the wing and are poor fertile and small body. we is discussed in 3 references, dated between 1935 and 1992.
}
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GENR
{
SUMX| The D. melanogaster gene wings down, abbreviated as wdn, is reported here. It encodes a product with RNA polymerase II transcription factor activity involved in regulation of transcription, DNA-dependent which is a component of the nucleus; it is expressed in the ovary (nurse cell and oocyte). It has been sequenced and its amino acid sequence contains a zinc finger, C2H2 type. It has been mapped cytologically to 98E5. There are 7 recorded alleles: 2 in vitro constructs (none available from the public stock centers), 4 classical mutants (none available from the public stock centers) and 1 wild-type. Mutations have been isolated which affect the maternal effect wing, the maternal effect anterior crossvein, the maternal effect posterior crossvein and 3 other listed tissues and are recessive visible and recessive maternal effect embryonic lethal. wdn is discussed in 18 references (excluding sequence accessions), dated between 1929 and 2003. These include at least 3 studies of mutant phenotypes and 5 molecular studies.
}
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GENR
{
SUMX| The D. melanogaster gene wavoid-like, abbreviated as wdl, is reported here. It has been mapped by recombination to 2-39 and cytologically to 31F2--32A2. There are 2 recorded alleles: 1 classical mutant (available from the public stock centers) and 1 wild-type. Mutations have been isolated which affect the wing and the wing vein L5 and are viable, female semi-sterile and maternal effect lethal. wdl is discussed in 12 references, dated between 1945 and 1998. These include at least one study of mutant phenotypes.
}
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GENR
{
SUMX| The D. melanogaster gene wavoid, abbreviated as wd, is reported here. It has been mapped by recombination to 2-40. There are 3 recorded alleles: 2 classical mutants (none available from the public stock centers) and 1 wild-type. Mutations have been isolated which affect the wing and are visible. wd is discussed in 3 references, dated between 1944 and 1992.
}
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GENR
{
SUMX| The D. melanogaster gene windbeutel, abbreviated as wbl, is reported here. It encodes a product involved in maternal determination of dorsal/ventral axis, oocyte, soma encoded which is a component of the endoplasmic reticulum; it is expressed in the ovary (follicle cell and ovary). It has been sequenced. It has been mapped by recombination to 2-86 and cytologically to 56C4. It interacts genetically with gd. There are 9 recorded alleles: 1 in vitro construct (not available from the public stock centers), 7 classical mutants (1 available from the public stock centers) and 1 wild-type. Mutations have been isolated which affect the embryo and are embryonic recessive non-rescuable maternal effect lethal. wbl is discussed in 73 references (excluding sequence accessions), dated between 1987 and 2004. These include at least 4 studies of mutant phenotypes, one study of wild-type function and 2 molecular studies. Among findings on wbl mutants, mutation in wbl results in a maternal effect phenotype with defects during the early stages of gastrulation and defects in the dorsoventral axis; embryos derived from homozygous females are dorsalized.
}
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GENR
{
SUMX| The D. melanogaster gene wing blister, abbreviated as wb, is reported here. It has also been known in FlyBase as BEST:CK02229 and CG15288. It encodes a product with binding involved in cell-cell signaling which is localized to the basal lamina; it is expressed in the embryo (alary cell, embryonic/larval visceral mesoderm, mesectoderm, muscle attachment site and 2 other listed tissues), larva (dorsal mesothoracic disc) and ovary (oocyte and nurse cell). It has been sequenced. It has been mapped by recombination to 2-50 and cytologically to 35A3--4. There are 60 recorded alleles: 59 classical mutants (3 available from the public stock centers) and 1 wild-type. Mutations have been isolated which affect the wing and are recessive lethal. wb is discussed in 73 references (excluding sequence accessions), dated between 1977 and 2004. These include at least one study of mutant phenotypes, 2 studies of wild-type function and 10 molecular studies. Among findings on wb function, wb is involved in processes requiring cell migration and cell adhesion.
}
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GENR
{
SUMX| The D. melanogaster gene waclaw, abbreviated as waw, is reported here. It has also been known in FlyBase as anon-19Fb. It encodes a product with translation elongation factor activity involved in protein biosynthesis. It has been sequenced and its amino acid sequence contains a GTP-binding elongation factor. There are 4 recorded alleles: 3 classical mutants (1 available from the public stock centers) and 1 wild-type. waw is discussed in 10 references (excluding sequence accessions), dated between 1993 and 2004. These include at least one study of wild-type function and 4 molecular studies.
}
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GENR
{
SUMX| The D. melanogaster gene warbler, abbreviated as war, is reported here. It encodes a product involved in nurse cell to ocyte transport (sensu Insecta). It has been mapped by recombination to 2-79. There are 2 recorded alleles: 1 classical mutant (available from the public stock centers) and 1 wild-type. Mutations have been isolated which are female sterile. war is discussed in one reference, dating from 1991.
}
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GENR
{
SUMX| The D. melanogaster gene wings apart mimic, abbreviated as wapm, is reported here. It has been mapped cytologically to 12D2--3. There are 2 recorded alleles: 1 classical mutant (not available from the public stock centers) and 1 wild-type. Mutations have been isolated which affect the wing and are viable and female fertile. wapm is discussed in one reference, dating from 1992.
}
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GENR
{
SUMX| The D. melanogaster gene wings apart-like, abbreviated as wapl, is reported here. It encodes a product involved in female meiosis chromosome segregation. It has been sequenced and its amino acid sequence is also available. It has been mapped by recombination to 1-0.7 and cytologically to 2D5. There are 34 recorded alleles: 3 in vitro constructs (none available from the public stock centers), 30 classical mutants (4 available from the public stock centers) and 1 wild-type. Mutations have been isolated which affect the germ-line clone maternal effect pre-blastoderm, the maternal effect heterochromatin and the maternal effect metaphase chromosome and are recessive lethal. wapl is discussed in 31 references (excluding sequence accessions), dated between 1973 and 2001. These include at least 2 studies of mutant phenotypes, one study of wild-type function and 7 molecular studies. Among findings on wapl mutants, mutations in wapl prevent the normal close apposition of sister chromatids in heterochromatic regions, but do not appear to affect either heterochromatin condensation or chromosome segregation. Among findings on wapl function, wapl controls heterochromatin organization.
}
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GENR
{
SUMX| The D. melanogaster gene wings apart, abbreviated as wap, is reported here. It has been mapped cytologically to 20A3--4. There are 12 recorded alleles: 11 classical mutants (1 available from the public stock centers) and 1 wild-type. Mutations have been isolated which affect the wing, the crossvein, the wing vein and the adult thorax and are recessive semi-lethal, pupal recessive lethal, body color defective and visible. wap is discussed in 32 references, dated between 1968 and 2004.
}
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GENR
{
SUMX| The D. melanogaster gene wanderer, abbreviated as wan, is reported here. It encodes a product involved in peripheral nervous system development. There are 3 recorded alleles: 2 classical mutants (1 available from the public stock centers) and 1 wild-type. Mutations have been isolated which affect the peripheral nervous system and are recessive lethal. wan is discussed in 2 references, dated between 1994 and 1997. These include at least one study of mutant phenotypes.
}
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GENR
{
SUMX| The D. melanogaster gene walrus, abbreviated as wal, is reported here. It has also been known in FlyBase as BcDNA:GH09945, BcDNA:LD07532, EP2253 and l(2)02516. It encodes a product with electron carrier activity involved in ectodermal gut morphogenesis which is a component of the electron transfer flavoprotein complex (sensu Eukarya). It has been sequenced. It has been mapped by recombination to 2-59 and cytologically to 48C1--2. There are 6 recorded alleles: 5 classical mutants (2 available from the public stock centers) and 1 wild-type. Mutations have been isolated which affect the embryonic maternal effect cuticle and are larval recessive lethal. wal is discussed in 19 references (excluding sequence accessions), dated between 1994 and 2004. These include at least one study of mutant phenotypes and 4 molecular studies.
}
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GENR
{
SUMX| The D. melanogaster gene walkabout, abbreviated as wako, is reported here. There are 3 recorded alleles: 2 classical mutants (none available from the public stock centers) and 1 wild-type. Loss-of-function mutations have been isolated which are recessive lethal and recessive neuroanatomy defective. wako is discussed in 7 references, dated between 1993 and 1995.
}
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GENR
{
SUMX| The D. melanogaster gene waddell, abbreviated as wad, is reported here. There are 2 recorded alleles: 1 classical mutant (not available from the public stock centers) and 1 wild-type. Mutations have been isolated which affect the cleavage. wad is discussed in 3 references, dated between 1994 and 2000.
}
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GENR
{
SUMX| The D. melanogaster gene warty, abbreviated as wa, is reported here. It has been mapped by recombination to 1-64.4. There are 5 recorded alleles: 4 classical mutants (none available from the public stock centers) and 1 wild-type. Mutations have been isolated which affect the eye, the ommatidium and the wing and are visible, partially male sterile and dominant partially female sterile. wa is discussed in 4 references, dated between 1950 and 1992.
}
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GENR
{
SUMX| The D. melanogaster/D. mauritiana fusion gene w::Dmau\w is reported here. There are 81 recorded alleles: 1 in vitro construct (not available from the public stock centers) and 80 classical mutants (none available from the public stock centers). w::Dmau\w is discussed in 8 references, dated between 1991 and 2002.
}
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GENR
{
SUMX| The D. melanogaster gene white, abbreviated as w, is reported here. It has also been known in FlyBase as MS:DMWHITE, MS:w.AT13 and e(g). It encodes a product with eye pigment precursor transporter activity involved in ommochrome biosynthesis which is a component of the integral to plasma membrane; it is expressed in the adult (head). It has been sequenced and its amino acid sequence contains a ABC transporter and a AAA ATPase superfamily. It has been mapped by recombination to 1-1.5 and cytologically to 3C1. It interacts genetically with z, mw, Doa, Inr-a, B52 and 48 other listed genes. There are 1493 recorded alleles: 434 in vitro constructs (14 available from the public stock centers), 1044 classical mutants (48 available from the public stock centers) and 15 wild-type. Amorphic mutations have been isolated which affect the pigment cell and are recessive visible and eye color defective. w is discussed in 2918 references (excluding sequence accessions), dated between 1910 and 2004. These include at least 101 studies of mutant phenotypes, 3 studies of wild-type function, 5 studies of natural polymorphisms and 13 molecular studies. Among findings on w mutants, transcriptional analysis of w^a demonstrates that the w promoter and the copia promoter are not coordinate in their dosage compensation abilities when assayed in larvae and adults in different genomic locations. Among findings on w function, several regions of the genome that act as dosage-dependent modifiers of w alleles have been identified. Among findings on w polymorphisms, these unusually large haplotype blocks are due to positive selection on polymorphisms within the w gene, including a replacement polymorphism (Leu for Arg).
}
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GENR
{
SUMX| The D. melanogaster gene ventral veins lacking, abbreviated as vvl, is reported here. It has also been known in FlyBase as prd3, u-turn and ut. It encodes a product with DNA binding involved in tracheal cell fate determination (sensu Insecta) which is a component of the nucleus; it is expressed in the embryo (RP neuron, abdominal 1 to 7 larval oenocyte group, central nervous system, ectoderm and 16 other listed tissues). It has been sequenced and its amino acid sequence contains a 'POU' domain and a homeobox domain. It has been mapped by recombination to 3-26 and cytologically to 65C5. It interacts genetically with Egfr, rho, N, dpp, tkv and 5 other listed genes. There are 25 recorded alleles: 7 in vitro constructs (none available from the public stock centers), 17 classical mutants (2 available from the public stock centers) and 1 wild-type. Loss-of-function mutations have been isolated which affect the embryonic/larval tracheal system, the embryonic nervous system, the mesectoderm and the wing vein and are dominant visible. vvl is discussed in 128 references (excluding sequence accessions), dated between 1986 and 2004. These include at least 26 studies of mutant phenotypes, 2 studies of wild-type function and 9 molecular studies. Among findings on vvl mutants, mutation in vvl causes abnormal positioning of the chordotonal organs. Among findings on vvl function, vvl may regulate dendritic targeting and coordinate dendritic and axonal connectivity of projection neurons in the olfactory system to ensure the highly stereotypes acquisition and delivery of olfactory information by the central olfactory neurons.
}
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GENR
{
SUMX| The D. melanogaster gene vesuvio, abbreviated as vu, is reported here. It encodes a product with molecular_function unknown involved in biological_process unknown which is a component of the cellular_component unknown. There is one recorded allele, which is wild-type. vu is discussed in 2 references, dated between 1999 and 2002.
}
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GENR
{
SUMX| The D. melanogaster gene vertical wings, abbreviated as vtw, is reported here. It encodes a product involved in muscle development. It has been mapped by recombination to 1-18 and cytologically to 5A8--C2. There are 3 recorded alleles: 2 classical mutants (1 available from the public stock centers) and 1 wild-type. Mutations have been isolated which affect the thorax, the dorsal medial muscle, the coxal tergal remotor muscle and 4 other listed tissues and are flightless and reduced viable. vtw is discussed in 6 references, dated between 1977 and 1997. These include at least 2 studies of mutant phenotypes.
}
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GENR
{
SUMX| The D. melanogaster gene verthandi, abbreviated as vtd, is reported here. It has also been known in FlyBase as l(3)80Fh. It has been mapped by recombination to 3-46 and cytologically to 80F. It interacts genetically with Pc, Antp, ph-p, mod(mdg4), hh and 2 other listed genes. There are 24 recorded alleles: 23 classical mutants (1 available from the public stock centers) and 1 wild-type. Mutations have been isolated which affect the macrochaeta, the eye, the sex comb and the wing and are recessive lethal. vtd is discussed in 26 references, dated between 1988 and 2003. These include at least 7 studies of mutant phenotypes.
}
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GENR
{
SUMX| The D. melanogaster gene vena transversa interrupta, abbreviated as vta, is reported here. There are 2 recorded alleles: 1 classical mutant (not available from the public stock centers) and 1 wild-type. vta is discussed in one reference, dating from 1947.
}
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GENR
{
SUMX| The D. melanogaster gene verticals, abbreviated as vt, is reported here. It has been mapped by recombination to 1-2.3 and cytologically to 3C5+. There is one recorded allele, which is wild-type. vt is discussed in 18 references, dated between 1965 and 2001.
}
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GENR
{
SUMX| The D. melanogaster gene vestar, abbreviated as vst, is reported here. It has been mapped by recombination to 2-4.3. There are 2 recorded alleles: 1 classical mutant (available from the public stock centers) and 1 wild-type. Mutations have been isolated which affect the wing and the eye and are poor viable and female sterile. vst is discussed in 2 references, dated between 1944 and 1992.
}
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GENR
{
SUMX| The D. melanogaster gene variable size and shape, abbreviated as vss, is reported here. There are 4 recorded alleles: 3 classical mutants (1 available from the public stock centers) and 1 wild-type. Mutations have been isolated which affect the egg and are maternal effect female sterile. vss is discussed in 3 references, dated between 1987 and 1992.
}
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GENR
{
SUMX| The D. melanogaster gene vesiculated, abbreviated as vs, is reported here. It has been mapped by recombination to 1-16.3 and cytologically to 6B2--3. It interacts genetically with rho. There are 20 recorded alleles: 19 classical mutants (2 available from the public stock centers) and 1 wild-type. Mutations have been isolated which affect the wing and are visible. vs is discussed in 28 references, dated between 1925 and 2001. These include at least one study of mutant phenotypes.
}
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GENR
{
SUMX| The D. melanogaster gene vrille, abbreviated as vri, is reported here. It has also been known in FlyBase as l(2)25Db and mat(2)ea-G. It encodes a product with transcription regulator activity involved in cell growth and/or maintenance which is a component of the nucleus; it is expressed in the adult (adult head, dorsal adult lateral neuron, photoreceptor cell and ventral adult lateral neuron), embryo (amnioserosa, anal pad, embryonic/larval foregut, embryonic/larval proventriculus and 6 other listed tissues), larva (embryonic/larval digestive system, imaginal disc, larval brain and larval lateral neuron) and ovary (follicle cell and nurse cell). It has been sequenced. It has been mapped by recombination to 2-17 and cytologically to 25D4--5. It interacts genetically with Mad, dpp, ea, Actn, bt and 2 other listed genes. There are 29 recorded alleles: 8 in vitro constructs (none available from the public stock centers), 20 classical mutants (1 available from the public stock centers) and 1 wild-type. Hypomorphic mutations have been isolated which affect the maternal effect wing vein L5 and the maternal effect wing vein L2 and are embryonic recessive non-rescuable maternal effect lethal and recessive female sterile. vri is discussed in 50 references (excluding sequence accessions), dated between 1988 and 2003. These include at least 4 studies of mutant phenotypes and 10 molecular studies.
}
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GENR
{
SUMX| The D. melanogaster gene varnished, abbreviated as vr, is reported here. It has been mapped by recombination to 3-44. There are 2 recorded alleles: 1 classical mutant (not available from the public stock centers) and 1 wild-type. Mutations have been isolated which affect the eye and the ommatidium and are female sterile. vr is discussed in 2 references, dated between 1923 and 1992.
}
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GENR
{
SUMX| The D. melanogaster gene venula, abbreviated as vnl, is reported here. There are 2 recorded alleles: 1 classical mutant (not available from the public stock centers) and 1 wild-type. Mutations have been isolated which affect the wing vein. vnl is discussed in 2 references, dated between 1951 and 1992.
}
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GENR
{
SUMX| The D. melanogaster gene ventral nervous system defective, abbreviated as vnd, is reported here. It has also been known in FlyBase as NK2. It encodes a product with transcription regulator activity involved in regulation of transcription, DNA-dependent which is a component of the nucleus; it is expressed in the embryo (U neuron, anterior embryonic/larval midgut, central nervous system, embryonic neuron and 9 other listed tissues). It has been sequenced and its amino acid sequence contains a homeobox domain. It has been mapped by recombination to 1-0.0 and cytologically to 1B10. It interacts genetically with D and SoxN. There are 42 recorded alleles: 8 in vitro constructs (none available from the public stock centers), 33 classical mutants (none available from the public stock centers) and 1 wild-type. Loss-of-function mutations have been isolated which affect the neuroblast NB7-1, the neuroblast MP2, the neuroblast NB2 to 3-2 and 7 other listed tissues and are embryonic recessive lethal. vnd is discussed in 144 references (excluding sequence accessions), dated between 1980 and 2004. These include at least 5 studies of mutant phenotypes, 5 studies of wild-type function and 11 molecular studies. Among findings on vnd mutants, most ventral neuroblasts do not form in vnd null mutant embryos, and those that do develop intermediate-like fates and not ventral fates. Among findings on vnd function, vnd is necessary and sufficient to induce ventral fates and repress intermediate fates in the embryonic central nervous system.
}
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GENR
{
SUMX| The D. melanogaster gene vein, abbreviated as vn, is reported here. It has also been known in FlyBase as l(3)10567 and l(3)L6A. It encodes a product with epidermal growth factor receptor binding involved in notum morphogenesis which is a component of the extracellular; it is expressed in the embryo (, Keilin's organ, amnioserosa, central nervous system and 11 other listed tissues), larva (dorsal metathoracic disc, eye-antennal disc, ventral thoracic disc, dorsal mesothoracic disc and scutum) and prepupa and pupa (wing cell). It has been sequenced. It has been mapped by recombination to 3-16.2 and cytologically to 64E12--F2. It interacts genetically with Egfr, rho, spi, bs, H and 17 other listed genes. There are 45 recorded alleles: 6 in vitro constructs (none available from the public stock centers), 38 classical mutants (3 available from the public stock centers) and 1 wild-type. Amorphic mutations have been isolated which affect the wing, the Keilin's organ, the embryonic larval midgut and 2 other listed tissues and are embryonic recessive lethal. vn is discussed in 176 references (excluding sequence accessions), dated between 1971 and 2004. These include at least 25 studies of mutant phenotypes, 8 studies of wild-type function and 4 molecular studies. Among findings on vn mutants, in vivo culture of mutant discs from genotypes that are normally embryonic lethal demonstrates vn is essential for wing disc growth.
}
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GENR
{
SUMX| The D. melanogaster gene visible mutation-3, abbreviated as vm3, is reported here. It has been mapped by recombination to 1-53.6. There are 2 recorded alleles: 1 classical mutant (not available from the public stock centers) and 1 wild-type. Mutations have been isolated which affect the wing. vm3 is discussed in one reference, dating from 1995.
}
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GENR
{
SUMX| The D. melanogaster gene visible mutation-2, abbreviated as vm2, is reported here. It has been mapped by recombination to 1-48.4. There are 2 recorded alleles: 1 classical mutant (not available from the public stock centers) and 1 wild-type. Mutations have been isolated which affect the wing. vm2 is discussed in one reference, dating from 1995.
}
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GENR
{
SUMX| The D. melanogaster gene visible mutation-1, abbreviated as vm1, is reported here. It has been mapped by recombination to 1-46.6. There are 2 recorded alleles: 1 classical mutant (not available from the public stock centers) and 1 wild-type. Mutations have been isolated which affect the wing. vm1 is discussed in one reference, dating from 1995.
}
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GENR
{
SUMX| The D. melanogaster gene valois, abbreviated as vls, is reported here. It encodes a product involved in pole plasm assembly. It has been mapped by recombination to 2-53 and cytologically to 38A6--E9. It interacts genetically with nos. There are 7 recorded alleles: 6 classical mutants (1 available from the public stock centers) and 1 wild-type. Mutations have been isolated which affect the maternal effect cellular blastoderm, the maternal effect embryonic/first instar larval cuticle, the maternal effect pole cell and 2 other listed tissues and are embryonic recessive maternal effect lethal, recessive female sterile, recessive grandchildless and maternal effect male sterile. vls is discussed in 69 references, dated between 1986 and 2004. These include at least 8 studies of mutant phenotypes and one study of wild-type function.
}
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GENR
{
SUMX| The D. melanogaster gene veins longitudinally shortened, abbreviated as vli, is reported here. There are 2 recorded alleles: 1 classical mutant (not available from the public stock centers) and 1 wild-type. Mutations have been isolated which affect the wing vein L2 and the wing vein L4 to 5 and are semidominant visible. vli is discussed in 2 references, dated between 1937 and 1992.
}
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GENR
{
SUMX| The D. melanogaster gene viking, abbreviated as vkg, is reported here. It has also been known in FlyBase as l(2)01209 and viking. It encodes a product with putative extracellular matrix structural constituent putatively involved in cytoskeleton organization and biogenesis which is a component of the collagen type IV; it is expressed in the embryo (embryonic/larval fat body and embryonic/larval hemocyte) and larva (embryonic/larval fat body). It has been sequenced and its amino acid sequence is also available. It has been mapped cytologically to 25C1. It interacts genetically with LanA, Cg25C, Dfd and zip. There are 22 recorded alleles: 21 classical mutants (2 available from the public stock centers) and 1 wild-type. Mutations have been isolated which are recessive lethal. vkg is discussed in 33 references (excluding sequence accessions), dated between 1994 and 2004. These include at least 3 studies of mutant phenotypes, 2 studies of wild-type function and 5 molecular studies.
}
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GENR
{
SUMX| The D. melanogaster repetitive element vivi-repeat is reported here. It has also been known in FlyBase as anon-EST:fe2A2 and anon-fe2A2. It has been sequenced. There is one recorded allele, which is wild-type. vivi-repeat is discussed in 5 references (excluding sequence accessions), dated between 1986 and 2002.
}
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GENR
{
SUMX| The D. melanogaster gene virilizer, abbreviated as vir, is reported here. It has also been known in FlyBase as CG3496. It encodes a product with nucleic acid binding involved in regulation of nuclear mRNA splicing, via spliceosome which is a component of the nucleus. It has been sequenced. It has been mapped by recombination to 2-103.3 and cytologically to 59D8--9. It interacts genetically with Sxl, mle, msl-1 to 2, Ubx and snf. There are 15 recorded alleles: 2 in vitro constructs (none available from the public stock centers), 12 classical mutants (none available from the public stock centers) and 1 wild-type. Mutations have been isolated which affect the adult conditional ts abdomen, the conditional ts abdominal tergite 6 to 7, the conditional ts oviprotector and 3 other listed tissues and are female conditional ts sex-determination defective and viable. vir is discussed in 31 references (excluding sequence accessions), dated between 1988 and 2003. These include at least 8 studies of mutant phenotypes and one molecular study.
}
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GENR
{
SUMX| The D. melanogaster gene vin is reported here. It has been mapped by recombination to 3-36.3 and cytologically to 68C8--D3. There are 6 recorded alleles: 5 classical mutants (none available from the public stock centers) and 1 wild-type. Mutations have been isolated which affect the pigment cell and are viable, fertile, recessive visible and eye color defective. vin is discussed in 8 references, dated between 1973 and 2001.
}
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GENR
{
SUMX| The D. melanogaster gene visceral mesodermal armadillo-repeats, abbreviated as vimar, is reported here. It has also been known in FlyBase as anon-EST:Posey213 and l(2)k16722. It encodes a product with Ral interactor activity putatively involved in intracellular signaling cascade. It has been sequenced. It has been mapped cytologically to 42E1--4. There are 7 recorded alleles: 6 classical mutants (1 available from the public stock centers) and 1 wild-type. Mutations have been isolated which are viable and fertile. vimar is discussed in 9 references (excluding sequence accessions), dated between 1990 and 2003. These include at least one study of wild-type function and 5 molecular studies.
}
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GENR
{
SUMX| The D. melanogaster gene vihar is reported here. It has also been known in FlyBase as CG10682. It encodes a product with ubiquitin conjugating enzyme activity putatively involved in protein metabolism. It has been sequenced. It has been mapped cytologically to 69C4. There is one recorded allele, which is wild-type. vihar is discussed in 8 references (excluding sequence accessions), dated between 1999 and 2004. These include at least one molecular study.
}
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GENR
{
SUMX| The D. melanogaster gene vasa intronic gene, abbreviated as vig, is reported here. It encodes a product with putative RNA binding involved in RNA interference which is a component of the RNA-induced silencing complex. It has been sequenced. It has been mapped cytologically to 35B10--C1. There are 6 recorded alleles: 3 in vitro constructs (none available from the public stock centers), 2 classical mutants (none available from the public stock centers) and 1 wild-type. vig is discussed in 19 references (excluding sequence accessions), dated between 1996 and 2004. These include at least 7 molecular studies.
}
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GENR
{
SUMX| The D. melanogaster gene visual system disorganizer, abbreviated as vid, is reported here. It has been mapped cytologically to 63C. There are 2 recorded alleles: 1 classical mutant (not available from the public stock centers) and 1 wild-type. Mutations have been isolated which affect the somatic clone optic lobe, the photoreceptor cell, the adult brain and 3 other listed tissues. vid is discussed in one reference, dating from 1997.
}
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GENR
{
SUMX| The D. melanogaster gene vibrator, abbreviated as vib, is reported here. It has also been known in FlyBase as CG5269. It encodes a product with phospholipid transporter activity putatively involved in intracellular protein transport. It has been sequenced. It has been mapped cytologically to 91F11--12. It interacts genetically with Egfr and sl. There are 3 recorded alleles: 2 classical mutants (none available from the public stock centers) and 1 wild-type. vib is discussed in 9 references (excluding sequence accessions), dated between 1999 and 2004. These include at least one study of mutant phenotypes, one study of wild-type function and one molecular study. Among findings on vib mutants, vib mutants show phenotypes in oogenesis (collapsed ring canals), bristle differentiation (unpigmented, flaccid bristles) and hair production (multiple hairs per cell). Among findings on vib function, vib has a number of roles throughout development.
}
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GENR
{
SUMX| The D. melanogaster gene vena interrupta, abbreviated as vi, is reported here. There are 2 recorded alleles: 1 classical mutant (not available from the public stock centers) and 1 wild-type. vi is discussed in one reference, dating from 1947.
}
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GENR
{
SUMX| The D. melanogaster gene vestigial, abbreviated as vg, is reported here. It encodes a product involved in wing morphogenesis which is localized to the nucleus; it is expressed in the embryo (abdomen, dorsal mesothoracic disc, dorsal metathoracic disc, dorsal prothoracic disc and 4 other listed tissues) and larva (dorsal mesothoracic disc and dorsal metathoracic disc). It has been sequenced and its amino acid sequence is also available. It has been mapped by recombination to 2-67.0 and cytologically to 49E1. It interacts genetically with N, wg, sd, M(3)80, ap and 23 other listed genes. There are 396 recorded alleles: 18 in vitro constructs (none available from the public stock centers), 377 classical mutants (10 available from the public stock centers) and 1 wild-type. Amorphic mutations have been isolated which affect the posterior scutellar bristle, the wing, the ectopic mesothoracic tergum and 5 other listed tissues and are female sterile and recessive visible. vg is discussed in 420 references (excluding sequence accessions), dated between 1919 and 2004. These include at least 39 studies of mutant phenotypes, 6 studies of wild-type function, one study of natural polymorphisms and 5 molecular studies. Among findings on vg mutants, the mutant phenotype of four vg alleles is suppressed when the alleles are stabilized in the P-cytotype.
}
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GENR
{
SUMX| The vertebrate gene Vvvv\c-Rel is reported here. It has also been known in FlyBase as vertebrate\c-Rel. There is one recorded allele, which is an in vitro construct not available from the public stock centers. Vvvv\c-Rel is discussed in one reference, dating from 1993.
}
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GENR
{
SUMX| The vertebrate gene Vvvv\Smad1 is reported here. It has also been known in FlyBase as vertebrate\Smad1. There are two recorded alleles, both in vitro constructs, neither available from the public stock centers. Vvvv\Smad1 is discussed in one reference, dating from 1999.
}
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GENR
{
SUMX| The D. melanogaster gene verfilzt is reported here. There are 2 recorded alleles: 1 classical mutant (not available from the public stock centers) and 1 wild-type. Mutations have been isolated which affect the embryonic central nervous system and the commissure. verfilzt is discussed in one reference, dating from 1999.
}
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GENR
{
SUMX| The D. melanogaster gene verrocchio, abbreviated as ver, is reported here. There is one recorded allele, which is wild-type. ver is discussed in one reference, dating from 1999.
}
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GENR
{
SUMX| The D. melanogaster gene venation, abbreviated as ven, is reported here. It has been mapped cytologically to 89C2. There are 3 recorded alleles: 2 classical mutants (none available from the public stock centers) and 1 wild-type. Mutations have been isolated which affect the wing vein, the wing vein L3, the crossvein and 2 other listed tissues and are small body and sterile. ven is discussed in 3 references, dated between 1937 and 1992.
}
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GENR
{
SUMX| The D. melanogaster gene vegetable, abbreviated as veg, is reported here. It has also been known in FlyBase as CG6657. It encodes a product involved in peripheral nervous system development which is putatively a component of the integral to membrane. It has been sequenced. It has been mapped cytologically to 53E2. There are 9 recorded alleles: 8 classical mutants (1 available from the public stock centers) and 1 wild-type. Mutations have been isolated which affect the embryonic peripheral nervous system and are embryonic recessive lethal. veg is discussed in 11 references (excluding sequence accessions), dated between 1994 and 2003. These include at least 3 molecular studies.
}
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GENR
{
SUMX| The D. melanogaster gene vena decussata, abbreviated as vd, is reported here. There are 2 recorded alleles: 1 classical mutant (not available from the public stock centers) and 1 wild-type. vd is discussed in one reference, dating from 1947.
}
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GENR
{
SUMX| The D. melanogaster gene ventral central gaps, abbreviated as vcg, is reported here. There are 2 recorded alleles: 1 classical mutant (not available from the public stock centers) and 1 wild-type. Mutations have been isolated which affect the longitudinal connective, the commissure and the abdominal 3 to 6 ventral denticle belt and are embryonic recessive lethal. vcg is discussed in one reference, dating from 1993.
}
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GENR
{
SUMX| The D. melanogaster gene vibrissae, abbreviated as vb, is reported here. It has been mapped by recombination to 1-49.3. There are 3 recorded alleles: 2 classical mutants (2 available from the public stock centers) and 1 wild-type. Mutations have been isolated which affect the vibrissae. vb is discussed in 8 references, dated between 1938 and 1998.
}
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GENR
{
SUMX| The D. melanogaster gene vasa, abbreviated as vas, is reported here. It has also been known in FlyBase as cgt and fs(2)ltoRJ36. It encodes a product with RNA helicase activity (EC:2.7.7.-) involved in pole plasm assembly which is localized to the cytoplasm; it is expressed in the adult (egg chamber and testis), embryo (pole cell and pole granule), larva (pole cell), ovary (female germline stem cell, germarium, nurse cell, oocyte and 2 other listed tissues), cyst cell, male germline stem cell and spermatocyte) and pole granule). It has been sequenced and its amino acid sequence contains a ATP-dependent helicase, DEAD-box, a DEAD/DEAH box helicase and a helicase C-terminal domain. It has been mapped by recombination to 2-51 and cytologically to 35B10--C1. It interacts genetically with nos, osk, exu, BicD, eIF5B and 2 other listed genes. There are 64 recorded alleles: 29 in vitro constructs (none available from the public stock centers), 34 classical mutants (2 available from the public stock centers) and 1 wild-type. Loss-of-function mutations have been isolated which affect the egg and the embryonic abdominal segment and are maternal effect male sterile, maternal effect female sterile and maternal effect recessive lethal. vas is discussed in 345 references (excluding sequence accessions), dated between 1986 and 2004. These include at least 18 studies of mutant phenotypes, 9 studies of wild-type function and 24 molecular studies. Among findings on vas mutants, mutations in vas cause failure of germ cell formation and deletions in the abdominal segments in the embryo. Among findings on vas function, vas is required for the establishment of both anterior-posterior and dorsal-ventral polarity of the oocyte. (However, there is much more information on function so that may not be representative.)
}
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GENR
{
SUMX| The D. melanogaster gene vacuolar peduncle, abbreviated as vap, is reported here. It has also been known in FlyBase as RasGAP and RasGap. It encodes a product with Ras GTPase activator activity involved in behavioral response to ethanol which is localized to the cytoplasm. It has been sequenced. It has been mapped by recombination to 1-54.2 and cytologically to 14A5--6. It interacts genetically with Egfr, Ras85D, drk, rho and sty. There are 9 recorded alleles: 4 in vitro constructs (none available from the public stock centers), 4 classical mutants (1 available from the public stock centers) and 1 wild-type. Mutations have been isolated which affect the adult brain and are recessive short lived. vap is discussed in 30 references (excluding sequence accessions), dated between 1979 and 2003. These include at least one study of mutant phenotypes, one study of wild-type function and 2 molecular studies. Among findings on vap function, vap can function as an inhibitor of signaling pathways mediated by Ras and receptor tyrosine kinases.
}
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GENR
{
SUMX| The D. melanogaster gene varied outspread, abbreviated as vao, is reported here. It has been mapped cytologically to 19E7. There are 4 recorded alleles: 3 classical mutants (none available from the public stock centers) and 1 wild-type. Mutations have been isolated which affect the wing and the pigment cell and are recessive male sterile, poor viable, eye color defective, visible and body color defective. vao is discussed in 21 references, dated between 1959 and 2004.
}
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GENR
{
SUMX| The D. melanogaster gene vacuolar medulla, abbreviated as vam, is reported here. It has been mapped by recombination to 1-50.6. There are 2 recorded alleles: 1 classical mutant (not available from the public stock centers) and 1 wild-type. Mutations have been isolated which affect the medulla, the lamina, the lobula and 2 other listed tissues and are neurophysiology defective, neuroanatomy defective and optomotor behavior defective. vam is discussed in 8 references, dated between 1979 and 1998.
}
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GENR
{
SUMX| The D. melanogaster gene ventral abdominal hole, abbreviated as vah, is reported here. There are 2 recorded alleles: 1 classical mutant (not available from the public stock centers) and 1 wild-type. Mutations have been isolated which affect the central nervous system, the prothoracic ventral denticle belt, the mesothoracic ventral denticle belt and 2 other listed tissues and are embryonic recessive lethal. vah is discussed in one reference, dating from 1993.
}
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GENR
{
SUMX| The D. melanogaster gene vacuolated, abbreviated as vac, is reported here. It has been mapped by recombination to 1-58.5 and cytologically to 19E7--8. There are 2 recorded alleles: 1 classical mutant (not available from the public stock centers) and 1 wild-type. Mutations have been isolated which affect the wing and are viable, fertile and recessive visible. vac is discussed in 2 references, dated between 1958 and 1992.
}
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GENR
{
SUMX| The D. melanogaster gene chromosome bows, abbreviated as chb, is reported here. It has also been known in FlyBase as BcDNA:LD31673, NEST:bs13a06, NEST:bs17d05, NEST:bs28g05, anon-WO0104295, mast, orbit and v40. It encodes a product with microtubule binding involved in mitosis which is localized to the microtubule; it is expressed in the adult (ovary) and larva (embryonic/larval brain). It has been sequenced. It has been mapped by recombination to 3-46.6 and cytologically to 78C1--2. It interacts genetically with ksr and Ras85D. There are 16 recorded alleles: 3 in vitro constructs (none available from the public stock centers), 12 classical mutants (none available from the public stock centers) and 1 wild-type. Amorphic mutations have been isolated which affect the mitotic cycle and the mitotic metaphase and are recessive mitotic. chb is discussed in 36 references (excluding sequence accessions), dated between 1997 and 2004. These include at least one study of mutant phenotypes, 4 studies of wild-type function and 5 molecular studies. Among findings on chb function, chb is required for stem cell and cystocyte divisions during oogenesis.
}
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GENR
{
SUMX| The D. melanogaster gene vermilion, abbreviated as v, is reported here. It encodes a product with tryptophan 2,3-dioxygenase activity (EC:1.13.11.11) involved in eye pigmentation (sensu Drosophila). It has been sequenced and its amino acid sequence is also available. It has been mapped by recombination to 1-33.0 and cytologically to 9F11. It interacts genetically with su(s), bw and w. There are 730 recorded alleles: 16 in vitro constructs (1 available from the public stock centers), 713 classical mutants (11 available from the public stock centers) and 1 wild-type. Hypomorphic mutations have been isolated which affect the pigment cell and the ocellus pigment granule and are recessive visible and eye color defective. v is discussed in 241 references (excluding sequence accessions), dated between}